NAD+ (β-nicotinamide adenine dinucleotide, disodium salt) — bulk research supply

Regulatory positioning: Nutraceutical / cosmetic grade. NAD+ (β-nicotinamide adenine dinucleotide, disodium salt) is supplied as nutraceutical / cosmetic grade reference material. Not a finished pharmaceutical product. Subject to buyer compliance with applicable supplement regulations.

Overview

NAD+ (β-nicotinamide adenine dinucleotide) is a small-molecule coenzyme central to cellular redox metabolism, supplied by SPK Pharma India in the disodium salt, lyophilized form for research use. The disodium salt is the more water-soluble and storage-stable form of the coenzyme, and is the form typically used as an analytical reference standard and as a research reagent in cell-based assays of NAD+-dependent pathways. SPK Pharma India supplies NAD+ in bulk research tiers (100 g, 500 g, 1 kg) for research laboratories, distributors, and contract manufacturers that require gram-scale reference material with full lot documentation. The product is supplied for research and analytical applications only.

Specifications

Research context

NAD+ is one of the most-studied research coenzymes in cellular metabolism, with central roles in redox reactions (NAD+/NADH), in NAD+-dependent deacetylase (sirtuin) activity, in poly-ADP-ribose polymerase (PARP) activity, and in NAD+-consuming signalling pathways. The disodium salt is the form typically used in cell-based assays of NAD+ supplementation, in vitro NAD+ quantification assays, and in analytical method development for LC-MS and HPLC-based quantification of NAD+ and its metabolites (NADH, NADP+, NADPH, nicotinamide, nicotinamide mononucleotide).

Bulk supply at the 100 g / 500 g / 1 kg scale is positioned for analytical reference-standard programmes, calibration curve preparation, and larger in-vitro research programmes that require substantial quantities of the same lot. The lot-matched COA documents the actual HPLC purity, the UV-Vis absorbance ratio (A₂₆₀/A₂₈₀, characteristic of pure NAD+), and the mass spectrometry identity. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The compound is supplied strictly for in-vitro research, analytical method development, and reference-standard work.

For researchers new to the compound, the standard analytical reference points are CAS 53-84-9 (free acid) / CAS 606-68-8 (disodium salt), the disodium salt form, the calculated molecular weight of 685.41 g/mol (disodium salt, anhydrous), the characteristic UV absorbance maximum at 260 nm, and the documented purity threshold (≥99% HPLC).

Packaging and supply

• 100 g research pack — for method development, calibration curve preparation, and small-batch analytical programmes. Standard MOQ: 1 pack.
• 500 g research pack — for ongoing research programmes with higher per-assay demand. Standard MOQ: 1 pack.
• 1 kg research pack — for reference-standard stock programmes and large in-vitro research programmes. Standard MOQ: 1 pack.
• Bulk pack — on application, for annual supply contracts and recurring orders.

Distributor pricing is available on application. Annual supply contracts with scheduled recurring dispatch are available for repeat buyers. Lead time for in-stock SKUs is typically 5 business days from purchase order confirmation; lead time for scheduled production is typically 4 to 6 weeks.

Quality and documentation

Every lot of NAD+ ships with a lot-matched Certificate of Analysis documenting identity (HPLC retention time, UV-Vis spectroscopy, and mass spectrometry), purity (HPLC), appearance, lot number, and synthesis batch reference. A representative sample of every lot is independently verified by a third-party analytical laboratory before release. MSDS is supplied with every shipment. The COA template, the lot-traceability workflow, and the third-party verification scope are documented on the Quality page.

Storage and handling

• Store at -20°C in the original sealed container.
• Protect from light and moisture. NAD+ is light-sensitive and hygroscopic.
• Allow the sealed container to reach room temperature before opening, to avoid condensation.
• Reconstitute in cold, sterile, low-endotoxin research-grade water or in a cold buffer at the working concentration required by the assay. NAD+ is more stable at low pH and at lower temperatures.
• Do not refreeze once reconstituted; aliquot and store at working concentration.
• For NAD+ quantification, avoid repeated freeze-thaw cycles and minimise time at room temperature.

Shipping

NAD+ is shipped lyophilized in sealed containers within temperature-validated packaging. International lanes are routed through dedicated life-science logistics partners with cold-chain handling. Standard dispatch is within 5 business days of purchase order confirmation. SPK Pharma India ships to the United States, the European Union, the United Kingdom, Canada, MENA, APAC, and LATAM. Full export documentation, including commercial invoice, packing list, certificate of origin, COA, and MSDS, is included with every shipment. Destination-specific documentation is supported on request.

Compliance

NAD+ (β-nicotinamide adenine dinucleotide, disodium salt) is supplied as nutraceutical / cosmetic grade reference material. Not a finished pharmaceutical product. Subject to buyer compliance with applicable supplement regulations. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The buyer is responsible for end-use classification in the destination jurisdiction and for compliance with applicable supplement, cosmetic, and ingredient regulations.

Lead form CTA

To request a wholesale quote for NAD+ disodium salt, contact the trade desk with the subject line "NAD+ wholesale quote" and your company details, expected volume, and destination country. Distributor pricing is available on application. The desk responds within one business day.

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