Semax research peptide — wholesale supply

For research use only · Not for human consumption · Not for veterinary use. This product is supplied for in-vitro research, analytical method development, and laboratory reference standard use only. Not approved for human or veterinary administration. Buyer is responsible for end-use classification in the destination jurisdiction.

Overview

Semax is a synthetic seven-amino-acid heptapeptide research compound developed at the Institute of Molecular Genetics of the Russian Academy of Sciences as a structural analogue of the adrenocorticotropic hormone (ACTH) fragment 4-10. The sequence is Met-Glu-His-Phe-Pro-Gly-Pro, with a Pro-Gly-Pro C-terminal extension that confers resistance to enzymatic degradation. Semax is supplied as a research-grade lyophilized peptide, intended for in-vitro melanocortin receptor research, neurotrophic pathway studies, and analytical method development. SPK Pharma India supplies Semax as a documented, lot-traceable research compound for distributors, contract manufacturers, and academic laboratories. The disambiguation from Selank, which shares the Pro-Gly-Pro C-terminal motif but has a different N-terminal sequence, is important for research buyers — the two compounds are not interchangeable in research applications.

Specifications

Research context

Semax is studied in cell-based research on melanocortin receptor (MCR) pathways, with the ACTH 4-10 backbone providing the structural basis for receptor-engagement studies on MC3R, MC4R, and MC5R, and for downstream neurotrophic factor expression studies in defined cell-based systems. In-vitro receptor-binding assays, cAMP signalling studies in MCR-expressing cell lines, and BDNF / NGF expression studies are typical research applications. The disambiguation from Selank is important: Selank is the tuftsin analogue (Thr-Lys-Pro-Arg-Pro-Gly-Pro) with an immunomodulatory research profile, while Semax is the ACTH 4-10 analogue (Met-Glu-His-Phe-Pro-Gly-Pro) with a melanocortin-receptor research profile.

The compound is also used in research contexts where the Pro-Gly-Pro C-terminal extension is the variable of interest, for example in studies of peptide stability against prolyl-endopeptidase cleavage. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The compound is supplied strictly for in-vitro research, analytical method development, and reference-standard work.

For researchers new to the compound, the standard analytical reference points are CAS 80714-61-0, the seven-amino-acid sequence MEHFPGP, the calculated molecular weight of 813.93 g/mol, the lyophilized powder form, and the documented purity threshold (≥99% HPLC).

Packaging and supply

• 30 mg research vial — for method development, cell-based assays, and reference-standard qualification. Standard MOQ: 5 vials.
• Bulk pack — on application, for annual supply contracts and recurring orders.

Distributor pricing is available on application. Annual supply contracts with scheduled recurring dispatch are available for repeat buyers. Lead time for in-stock SKUs is typically 5 business days from purchase order confirmation; lead time for scheduled production is typically 4 to 6 weeks.

Quality and documentation

Every lot of Semax ships with a lot-matched Certificate of Analysis documenting identity (mass spectrometry and amino acid analysis), purity (HPLC), appearance, lot number, and synthesis batch reference. A representative sample of every lot is independently verified by a third-party analytical laboratory before release. MSDS is supplied with every shipment. The COA template, the lot-traceability workflow, and the third-party verification scope are documented on the Quality page.

Storage and handling

• Store at -20°C in the original sealed container.
• Protect from light and moisture.
• Allow the sealed container to reach room temperature before opening, to avoid condensation.
• Reconstitute in sterile, low-endotoxin research-grade water or in a mild buffer at the working concentration required by the assay.
• Do not refreeze once reconstituted; aliquot and store at working concentration.
• The Met residue is mildly oxidation-sensitive; avoid prolonged exposure to ambient air after reconstitution.

Shipping

Semax is shipped lyophilized in sealed vials within temperature-validated packaging. International lanes are routed through dedicated life-science logistics partners with cold-chain handling. Standard dispatch is within 5 business days of purchase order confirmation. SPK Pharma India ships to the United States, the European Union, the United Kingdom, Canada, MENA, APAC, and LATAM. Full export documentation, including commercial invoice, packing list, certificate of origin, COA, and MSDS, is included with every shipment. Destination-specific documentation is supported on request.

Compliance

This product is supplied for research use only. It is not a drug, not a finished dosage form, and not approved for human or veterinary administration. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The buyer is responsible for end-use classification in the destination jurisdiction and for ensuring that downstream handling is consistent with research-use-only protocols.

Lead form CTA

To request a wholesale quote for Semax, contact the trade desk with the subject line "Semax wholesale quote" and your company details, expected volume, and destination country. Distributor pricing is available on application. The desk responds within one business day.

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