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peptides

GHK-Cu (Copper Tripeptide-1) research compound — wholesale

SPK-GHK-012 · ≥99% HPLC
B2B only · Drug license required for trade · Rx against valid prescription · Subject to Drugs & Cosmetics Act 1940 & DGFT
Research use only Regulatory positioning

For research and laboratory use only. Not approved as a drug, medical device, or diagnostic agent in any jurisdiction. Not for human or veterinary use.

Specifications

Attribute Value
Molecular formulaC₁₂H₂₁CuN₆O₃
SequenceGly-His-Lys (3 amino acids) complexed with Cu²⁺
Molecular weight403.93 g/mol (as the GHK:Cu complex)
CAS89030-95-5
Purity≥99% HPLC
FormLyophilized powder (blue, characteristic of the copper complex)
Packaging50 mg · 100 mg · bulk on request
Storage-20°C, protected from light and moisture
Regulatory positioningFor research and laboratory use only. Not approved as a drug, medical device, or diagnostic agent in any jurisdiction. Not for human or veterinary use.

For research use only · Not for human consumption · Not for veterinary use. This product is supplied for in-vitro research, analytical method development, and laboratory reference standard use only. Not approved for human or veterinary administration. Buyer is responsible for end-use classification in the destination jurisdiction.

Overview

GHK-Cu is the copper-bound tripeptide Gly-His-Lys, also referenced as Copper Tripeptide-1 or the GHK copper complex. The tripeptide is a naturally occurring fragment of the alpha-2 chain of type I collagen, and the copper-complex form is the species that has been the most extensively studied in cell-based research. The compound is supplied as a research-grade lyophilized powder with the characteristic blue colour of the Cu²⁺ complex, intended for in-vitro cell-based assays of extracellular matrix remodelling, copper-dependent enzyme cofactor activity, and analytical reference-standard work. SPK Pharma India supplies GHK-Cu for research and analytical applications only, with the 50 mg and 100 mg vial formats positioned for in-vitro research laboratories, distributors, and contract manufacturers.

Specifications

Parameter Value
Compound name GHK-Cu (Copper Tripeptide-1)
Synonyms Gly-His-Lys copper complex, GHK copper, copper tripeptide
Compound class Tripeptide–metal complex (Cu²⁺)
CAS number 89030-95-5
Molecular formula C₁₂H₂₁CuN₆O₃
Molecular weight 403.93 g/mol
Amino acid count 3 residues (Gly-His-Lys)
Copper content Stoichiometric Cu²⁺ in the GHK:Cu complex
Appearance Blue to pale blue lyophilized powder (characteristic of the Cu²⁺ complex)
Purity ≥99% by HPLC
Identity Confirmed by mass spectrometry, UV-Vis spectroscopy, and amino acid analysis
Form Lyophilized powder
Packaging 50 mg vial · 100 mg vial · bulk on request
Storage -20°C, protected from light and moisture
Shelf life 24 months from manufacture date, stored as recommended
Intended use Research use only — not for human or veterinary use

Research context

GHK-Cu has been studied in cell-based research on extracellular matrix remodelling, the role of copper as a cofactor for lysyl oxidase and related enzymes, and the influence of the tripeptide on cell migration and matrix metalloproteinase activity in defined cell-based systems. The Cu²⁺ complex is the active research species, and the stoichiometry of the complex is confirmed by UV-Vis spectroscopy (the d-d transition around 600 nm is characteristic of the GHK:Cu complex).

The compound is also used as an analytical reference standard for LC-MS and HPLC method development in laboratories that study copper-peptide complexes, matrix metalloproteinase activity, and collagen biosynthesis. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The compound is supplied strictly for in-vitro research, analytical method development, and reference-standard work.

For researchers new to the compound, the standard analytical reference points are CAS 89030-95-5, the three-amino-acid sequence, the stoichiometric Cu²⁺ complex, the calculated molecular weight of 403.93 g/mol, the characteristic blue colour of the lyophilized powder, and the documented purity threshold (≥99% HPLC).

Packaging and supply

  • 50 mg research vial — for method development, cell-based assays, and reference-standard qualification. Standard MOQ: 5 vials.
  • 100 mg research vial — for ongoing research programmes with higher per-assay demand. Standard MOQ: 2 vials.
  • Bulk pack — on application, for annual supply contracts and recurring orders.

Distributor pricing is available on application. Annual supply contracts with scheduled recurring dispatch are available for repeat buyers. Lead time for in-stock SKUs is typically 5 business days from purchase order confirmation; lead time for scheduled production is typically 4 to 6 weeks.

Quality and documentation

Every lot of GHK-Cu ships with a lot-matched Certificate of Analysis documenting identity (mass spectrometry, UV-Vis spectroscopy, and amino acid analysis), purity (HPLC), appearance, lot number, and synthesis batch reference. A representative sample of every lot is independently verified by a third-party analytical laboratory before release. MSDS is supplied with every shipment. The COA template, the lot-traceability workflow, and the third-party verification scope are documented on the Quality page.

Storage and handling

  • Store at -20°C in the original sealed container.
  • Protect from light and moisture. The Cu²⁺ complex is light-sensitive; prolonged exposure to ambient light may affect the complex.
  • Allow the sealed container to reach room temperature before opening, to avoid condensation.
  • Reconstitute in sterile, low-endotoxin research-grade water or in a mild buffer at the working concentration required by the assay. Avoid strong chelators (EDTA) in the reconstitution buffer, as they will compete with GHK for Cu²⁺.
  • Do not refreeze once reconstituted; aliquot and store at working concentration.

Shipping

GHK-Cu is shipped lyophilized in sealed vials within temperature-validated packaging. International lanes are routed through dedicated life-science logistics partners with cold-chain handling. Standard dispatch is within 5 business days of purchase order confirmation. SPK Pharma India ships to the United States, the European Union, the United Kingdom, Canada, MENA, APAC, and LATAM. Full export documentation, including commercial invoice, packing list, certificate of origin, COA, and MSDS, is included with every shipment. Destination-specific documentation is supported on request.

Compliance

This product is supplied for research use only. It is not a drug, not a finished dosage form, and not approved for human or veterinary administration. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The buyer is responsible for end-use classification in the destination jurisdiction and for ensuring that downstream handling is consistent with research-use-only protocols.

Lead form CTA

To request a wholesale quote for GHK-Cu, contact the trade desk with the subject line "GHK-Cu wholesale quote" and your company details, expected volume, and destination country. Distributor pricing is available on application. The desk responds within one business day.

Related compounds

Request a quote for GHK-Cu (Copper Tripeptide-1)

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