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peptides

Kisspeptin-10 research peptide — wholesale supply

SPK-KIS-016 · ≥99% HPLC
B2B only · Drug license required for trade · Rx against valid prescription · Subject to Drugs & Cosmetics Act 1940 & DGFT
Research use only Regulatory positioning

For research and laboratory use only. Not approved as a drug, medical device, or diagnostic agent in any jurisdiction. Not for human or veterinary use.

Specifications

Attribute Value
Molecular formulaC₆₃H₈₁N₁₇O₁₄
SequenceTyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (10 amino acids; YNWNSFGLRF; amidated C-terminus)
Molecular weight1,302.45 g/mol
CAS374675-77-9
Purity≥99% HPLC
FormLyophilized powder
Packaging5 mg · bulk on request
Storage-20°C, protected from light and moisture
Regulatory positioningFor research and laboratory use only. Not approved as a drug, medical device, or diagnostic agent in any jurisdiction. Not for human or veterinary use.

For research use only · Not for human consumption · Not for veterinary use. This product is supplied for in-vitro research, analytical method development, and laboratory reference standard use only. Not approved for human or veterinary administration. Buyer is responsible for end-use classification in the destination jurisdiction.

Overview

Kisspeptin-10 (KP-10) is a synthetic ten-amino-acid research peptide corresponding to the C-terminal decapeptide of the Kisspeptin-1 (KISS1) precursor protein. The sequence is Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2, with an amidated C-terminus. KP-10 is the minimal peptide fragment that retains binding affinity for the KISS1 receptor (KISS1R, also known as GPR54), and the compound is supplied for in-vitro KISS1R receptor research, GPR54 signalling studies, and analytical method development. SPK Pharma India supplies Kisspeptin-10 as a documented, lot-traceable research compound for distributors, contract manufacturers, and academic laboratories.

Specifications

Parameter Value
Compound name Kisspeptin-10
Synonyms KP-10, Kisspeptin-10, metastin (10-54) C-terminal decapeptide
Compound class Synthetic 10-amino-acid KISS1R agonist
CAS number 374675-77-9
Molecular formula C₆₃H₈₁N₁₇O₁₄
Molecular weight 1,302.45 g/mol
Amino acid count 10 residues
C-terminus Amidated (-NH₂)
Appearance White to off-white lyophilized powder
Purity ≥99% by HPLC
Identity Confirmed by mass spectrometry and amino acid analysis
Form Lyophilized powder
Packaging 5 mg vial · bulk on request
Storage -20°C, protected from light and moisture
Shelf life 24 months from manufacture date, stored as recommended
Intended use Research use only — not for human or veterinary use

Research context

Kisspeptin-10 is studied in cell-based research on the KISS1 receptor (KISS1R / GPR54), a G-protein-coupled receptor that signals through the Gq/11 pathway, with downstream effects on intracellular calcium release, phospholipase C activation, and ERK1/2 phosphorylation in defined cell-based systems. In-vitro receptor-binding assays, calcium-flux assays, and downstream signalling studies in KISS1R-expressing cell lines are the typical research applications.

The minimal decapeptide form (KP-10) is the most commonly used research reagent in the Kisspeptin family, because it retains the full receptor-binding affinity of the longer Kisspeptin-54 (KP-54) precursor while being more tractable for synthesis and analytical work. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The compound is supplied strictly for in-vitro research, analytical method development, and reference-standard work.

For researchers new to the compound, the standard analytical reference points are CAS 374675-77-9, the ten-amino-acid sequence YNWNSFGLRF, the amidated C-terminus, the calculated molecular weight of 1,302.45 g/mol, the lyophilized powder form, and the documented purity threshold (≥99% HPLC).

Packaging and supply

  • 5 mg research vial — for method development, receptor-binding assays, and reference-standard qualification. Standard MOQ: 5 vials.
  • Bulk pack — on application, for annual supply contracts and recurring orders.

Distributor pricing is available on application. Annual supply contracts with scheduled recurring dispatch are available for repeat buyers. Lead time for in-stock SKUs is typically 5 business days from purchase order confirmation; lead time for scheduled production is typically 4 to 6 weeks.

Quality and documentation

Every lot of Kisspeptin-10 ships with a lot-matched Certificate of Analysis documenting identity (mass spectrometry and amino acid analysis), purity (HPLC), appearance, lot number, and synthesis batch reference. A representative sample of every lot is independently verified by a third-party analytical laboratory before release. MSDS is supplied with every shipment. The COA template, the lot-traceability workflow, and the third-party verification scope are documented on the Quality page.

Storage and handling

  • Store at -20°C in the original sealed container.
  • Protect from light and moisture. The Trp residue is mildly light-sensitive.
  • Allow the sealed container to reach room temperature before opening, to avoid condensation.
  • Reconstitute in sterile, low-endotoxin research-grade water or in a mild buffer at the working concentration required by the assay.
  • Do not refreeze once reconstituted; aliquot and store at working concentration.
  • For short peptides, gentle mixing is sufficient; avoid vigorous vortexing.

Shipping

Kisspeptin-10 is shipped lyophilized in sealed vials within temperature-validated packaging. International lanes are routed through dedicated life-science logistics partners with cold-chain handling. Standard dispatch is within 5 business days of purchase order confirmation. SPK Pharma India ships to the United States, the European Union, the United Kingdom, Canada, MENA, APAC, and LATAM. Full export documentation, including commercial invoice, packing list, certificate of origin, COA, and MSDS, is included with every shipment. Destination-specific documentation is supported on request.

Compliance

This product is supplied for research use only. It is not a drug, not a finished dosage form, and not approved for human or veterinary administration. SPK Pharma India does not make therapeutic, clinical, diagnostic, or dosing claims for this product. The buyer is responsible for end-use classification in the destination jurisdiction and for ensuring that downstream handling is consistent with research-use-only protocols.

Lead form CTA

To request a wholesale quote for Kisspeptin-10, contact the trade desk with the subject line "Kisspeptin-10 wholesale quote" and your company details, expected volume, and destination country. Distributor pricing is available on application. The desk responds within one business day.

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Request a quote for Kisspeptin-10

Quote requests answered within one business day. Volume pricing for recurring orders.

B2B only. By submitting this form you confirm you are a licensed trade buyer, registered manufacturer, or authorised healthcare professional. Trade subject to drug license verification and the Drugs & Cosmetics Act 1940.